Ningbo Micro-tube Polymer Materials Co., Ltd.
Ningbo Micro-tube Polymer Materials Co., Ltd.
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Multi-lumen Consumable Tubing
  • Multi-lumen Consumable TubingMulti-lumen Consumable Tubing

Multi-lumen Consumable Tubing

High-Performance Liquid Chromatography (HPLC) is a powerful analytical technique used to separate, identify and quantify components in a mixture. Multi-lumen Consumable Tubing can effectively improve the efficiency of fluid delivery in HPLC. Multi-lumen Consumable Tubing consists of multiple parallel channels or lumens within a single tube structure. This design allows it to deliver different fluids or gases simultaneously, thereby optimizing the overall performance of the HPLC system.

Multi-lumen Consumable Tubing is a specialized type of tubing that incorporates multiple internal channels or lumens. These lumens can be arranged in various configurations, such as parallel, concentric, or spiral, depending on the specific application requirements. The material composition of multi-lumen tubing can vary, but PEEK (Polyether Ether Ketone) is a particularly popular choice due to its excellent chemical resistance, mechanical strength, and flexibility.


Key Features of Multi-lumen Consumable Tubing


Simultaneous Fluid Transport: Multi-lumen tubing allows for the simultaneous transportation of multiple fluids or gases within a single tubing structure. This eliminates the need for multiple separate tubing lines, thereby simplifying the overall system design and reducing the risk of leaks or cross-contamination.

Space Efficiency: By consolidating multiple fluid pathways into a single tubing structure, multi-lumen tubing saves valuable space within the HPLC system. This can be particularly beneficial in compact or space-constrained applications.

Enhanced Flexibility: Multi-lumen tubing is often designed to be highly flexible, allowing for easy routing and manipulation within complex HPLC systems. This flexibility can also help to minimize pressure losses and maintain consistent flow rates.

Cost-Effective: By reducing the need for multiple separate tubing lines, multi-lumen tubing can help to lower overall system costs. Additionally, the durability and long-lasting nature of PEEK and other high-performance materials used in multi-lumen tubing can further reduce long-term maintenance and replacement costs.

Applications of Multi-lumen Consumable Tubing in HPLC


Multi-lumen Consumable Tubing is used in various parts of HPLC systems, including:


Sample Injection: Multi-lumen Consumable Tubing can be used in sample loops and injection systems to simultaneously transport sample fluid and diluent or buffer solutions. This can help to improve the precision and accuracy of sample injection.

Gradient Mixing: In HPLC systems that utilize gradient elution, multi-lumen tubing can be used to transport different solvent components to the mixing chamber. This allows for precise control over the solvent composition and gradient profile, thereby enhancing the separation efficiency and resolution of the analytical process.

Temperature Control: Multi-lumen tubing can also be used to transport cooling or heating fluids to various components within the HPLC system. This can help to maintain consistent temperatures and reduce thermal gradients, which can improve the accuracy and reproducibility of analytical results.

Advantages of Multi-lumen Consumable Tubing


Increased Efficiency: By consolidating multiple fluid pathways into a single tubing structure, multi-lumen tubing can help to streamline the overall HPLC process and increase overall system efficiency.

Improved Precision: The ability to simultaneously transport multiple fluids with precise control over flow rates and compositions can help to improve the precision and accuracy of HPLC analyses.

Cost Savings: The use of multi-lumen tubing can help to reduce overall system costs by eliminating the need for multiple separate tubing lines and lowering long-term maintenance and replacement costs.


Common HPLC Multi-lumen Consumable Tubing Sizes

Multi-lumen Consumable Tubing is available in various sizes to accommodate different HPLC system requirements, including flow rates, pressure ratings, and specific applications. The most common sizes of PEEK tubing for HPLC are defined by their inner diameter (ID) and outer diameter (OD).

Common Multi-lumen Consumable Tubing Sizes

  1. Inner Diameter (ID)

    • 0.005 inches (0.13 mm):
      • Use: Ideal for low-flow applications, such as microbore HPLC or when precise sample injection is needed.
    • 0.010 inches (0.25 mm):
      • Use: Common in standard analytical HPLC systems for regular flow rates.
    • 0.020 inches (0.50 mm):
      • Use: Suitable for applications requiring higher flow rates or for connecting larger volume components.
    • 0.030 inches (0.75 mm):
      • Use: Used for preparative HPLC where larger sample volumes and higher flow rates are needed.
    • 0.040 inches (1.00 mm):
      • Use: Common in semi-preparative and preparative HPLC systems, where high flow rates are typical.
  2. Outer Diameter (OD)

    • 1/32 inch (0.79 mm):
      • Use: Used in applications requiring very small bore tubing, such as microbore HPLC.
    • 1/16 inch (1.59 mm):
      • Use: The most common outer diameter for PEEK tubing in analytical HPLC, suitable for a wide range of applications.
    • 1/8 inch (3.18 mm):
      • Use: Used in preparative HPLC and other high-flow applications.

Selecting the Right Size

When selecting Multi-lumen Consumable Tubing for HPLC, consider the following factors:

  • Flow Rate: Smaller ID tubing is better for low flow rates, while larger ID tubing is needed for higher flow rates.
  • Pressure Rating: Tubing with a smaller ID can typically withstand higher pressures.
  • System Compatibility: Ensure the OD of the tubing matches the fittings and connections in your HPLC system.

Pressure Ratings

  • 0.005 inches ID with 1/16 inch OD: Up to 5000 psi
  • 0.010 inches ID with 1/16 inch OD: Up to 4000 psi
  • 0.020 inches ID with 1/16 inch OD: Up to 3000 psi
  • Larger IDs or ODs: Typically rated lower, depending on the exact dimensions.

These sizes cover a broad range of HPLC applications, from high-precision analytical work to high-volume preparative separations.

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